Research: Carbon Hemoperfusion Effects on Reducing NSAID Plasma Concentrations in Dogs with NSAID Toxicity
A new study highlights the high clinical efficacy of carbon hemoperfusion (HP) for treating NSAID toxicosis in dogs.
Title: Plasma Non-Steroidal Anti-Inflammatory Drug Concentrations During Carbon Hemoperfusion in 18 Dogs with Non-Steroidal Anti-Inflammatory Drug Toxicosis
Authors: Her J1,2, Butty EM3, Barnes J4, Tai C3, Labato MA3, Langston CE1
- College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA
- College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA
- Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA, USA
- ImmutriX Therapeutics, Inc, 3620 Homestead Street, Rapid City, SD, USA
Presented At: Renal Week 2025
A new study highlights the high clinical efficacy of carbon hemoperfusion (HP) for treating NSAID toxicosis in dogs. The study included 18 canine patients who ingested various NSAIDS (ibuprofen, carprofen, naproxen, meloxicam) and were treated with carbon HP alone or in combination with dialysis. Carbon HP significantly reduced NSAID concentrations in the plasma. Researchers also noted that carbon HP was more effective than dialysis in NSAID removal and recommended not using dialysis alone to treat these intoxications due to a less efficient extraction ratio.
